Ja-Hyoung Ryu
UNIST
Professor
South Korea
B.S., 2000, Yonsei University; Ph.D., 2006, Yonsei University; Postdoctoral Training, 2007-2011, University of Massachusettes Amherst (advisor: S. Thayumanavan); Assistant Professor, 2012-2016, Ulsan National Institute of Science and Technology (UNIST) ; Associate Professor (Tenured), 2016-2021, UNIST; Professor, 2021-present, UNIST
D. Kim, G. Yang, C. Lim, G. Park, J. Lee, Y. Sim, J.-H. Ryu* "Cancer Specific CAIX-Targeting Supramolecular Lysosome-Targeting Chimeras (Supra-LYTAC) for Targeted Protein Degradation" Adv. Sci. 2025, 2503134
J. Y. Oh, B. Jana, J. Seong, E.K. An, E. M. Go, S. Jin, H. W. Ok, M.-S. Seu, J.-h. Bae, C. Lee, S. Lee, T.-K. Kwon, J. K. Seo, E. Choi, S. K. Kwak,* M. S. Lah,* J.-H. Ryu* "Unveiling the Power of Cloaking Metal-organic Framework Platforms via Supramolecular Antibody Conjugation" ACS Nano, 2024, 18, 15790–15801
S. Kim‡, J.-B. Chae‡, D. Kim‡, C.-W. Park, Y. Sim, J. Kim, H. Lee, G. Park, J. Lee, S. Hong, B. Jana, C. Kim, H. Chung,* J.-H. Ryu* "Supramolecular Senolytics via Intracellular Oligomerization of Peptides in Response to Elevated Reactive Oxygen Species Levels in Aging Cells" J. Am. Chem. Soc. 2023, 145, 21991-22008
B. Jana‡, S. Jin‡, E. M. Go, Y. Cho, D. Kim, S. Kim, S. K. Kwak,* J.-H. Ryu* "Intra-Lysosomal Peptides Assembly for the High Selectivity Index against Cancer", J. Am. Soc. Chem. 2023, 145, 18414-18431
E. S. Choi‡, S. Kim‡, D. Kim, E. Choi*, J.-H. Ryu* "Drug-Loaded Nanogel for Efficient Orchestration of Cell Death Pathways by Intramitochondrial Disulfide Polymerization" Small 2023, 2308872
M. T. Jeena†, S. Jin†, K. Jeong, Y.i Cho, J. C. Kim, J. Lee, S. Lee, S.-W. Hwang, S. K. Kwak,* S. Kim,* J.-H. Ryu,* "Cancer-Selective Supramolecular Chemotherapy by Disassembly-Assembly Approach" Adv. Funct. Mater, 2022, 32, 2208098
H. Choi†, G. Park†, E. Shin, S. W. Shin, B. Jana, S. Jin, S. Kim, H. Wang, S. K. Kwak*, B. Xu*, J.-H. Ryu* "Intramitochondrial Co-assembly between ATP and Nucleopeptide Induces Cancer Cell Apoptosis" Chem. Sci. 2022, 13, 6197
Y. Jeong,* S. Jin, L. Palanikumar, H. Choi, E. Shin, E. M. Go, C. Keum, S. Bang, D. Kim, S. Lee, M. Kim, H. Kim, K. H. Lee, B. Jana, M.-H. Park, S. K. Kwak,* C. Kim,* J.-H. Ryu* "Stimuli-Responsive Adaptive Nanotoxin to Directly Penetrate the Cellular Membrane by Molecular Folding and Unfolding" J.Am. Chem. Soc. 2022 144, 5503.
Peptide synthesis, assembly characterization, drug delivery system
