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Doron Shabat

Doron Shabat

Tel Aviv University

Professor

Israel

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Chemiluminsence, Molecular sensores, Bioorganic chemistry

ACADEMIC CAREER

1987-1990 Technion, Haifa, Israel Chemistry B.Sc 1990-1997 Technion, Haifa, Israel Organic Chemistry Ph.D 1997-2000 The Scripps Research Institute, La Jolla, Ca. Research-Associate 2000-2004 Tel-Aviv University Senior Lecturer 2004-2005 Tel-Aviv University Senior Lecturer (Tenure) 2005-2009 Tel-Aviv University Associate Professor 2009-2016 Tel-Aviv University Full Professor 2016-Present Tel-Aviv University The Emerico Letay Chair of Chemical Processes

SELECTED PUBLICATIONS
  • David, M., Leirikh, T., Naama, N., Kopp, T., Shabat, D., “Phenylamine-1,2-Dioxetanes: Promising Class of Chemiluminescent Luminophores for Aqueous Sensing and Bacterial Detection”, Angew. Chem. Int. Ed., 2025, doi.org/10.1002/anie.202515674.

  • David, M., Gutkin, S., Nithun, R.V., Jbara, M., Shabat., “Unprecedented Photoinduced-Electron-Transfer Probe with a Turn-ON Chemiluminescence Mode-of-Action”, Angew. Chem., 2024, e202417924.

  • Shelef, O., Kopp, T., Tannous, T., Jospe-Kaufman, M., Arutkin, M., Reuveni, S., Shabat, D., Fridman, M. “Enzymatic Activity Profiling Using an Ultra-Sensitive Array of Chemiluminescent Probes for Bacterial Classification and Characterization”, J. Am. Chem. Soc., 2024, 146, 5263–5273.

  • Tannous, R., Shelef, O., Gutkin, S., David, M., Leirikh, T., Ge, L., Jaber, J., Zhou, Q., Ma, P., Fridman, M., Spitz, U., Houk, K.N., Shabat, D., “Spirostrain-Accelerated Chemiexcitation of Dioxetanes Yields Unprecedented Detection Sensitivity in Chemiluminescence Bioassays”, ACS. Cent. Sci., 2024, 10, 28–42.

  • Hananya, N., Shabat, D., “Recent Advances and Challenges in Luminescent Imaging: Bright Outlook for Chemiluminescence of Dioxetanes in Water”, ACS Central Sci., 2019, 5, 949-59.

  • Green, O., Eilon, T., Hananya, N., Gutkin, S., Bauer, CR., Shabat, D. “Opening a Gateway for Chemiluminescence Cell Imaging: Distinctive Methodology for Design of Bright Chemiluminescent Dioxetane Probes”, ACS Cent. Sci., 2017, 4, 349-58.

WHY MY LAB?

My lab has expertise in the design and synthesis of highly efficient chemiluminescence probes for enzymatic detection and molecular imaging.

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