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Fan Zhang

Fan Zhang

Fudan University

Deputy Dean

China

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Rare earth luminescent nanomaterials, NIR, Biomedical analysis

ACADEMIC CAREER

B.S., 2002, East China University of Science and Technology; M.S., 2005, Shanghai Normal University(advisor: Shiping Yang); Ph.D., 2008, Fudan University(advisor: Dongyuan Zhao); Postdoctoral Training, 2008-2010, University of California, Santa Barbara(advisor: Galen Stucky); Associate Professor, 2010-2013, Fudan University; Professor, 2013-present, Fudan University

SELECTED PUBLICATIONS
  • Near-infrared spatiotemporal color vision in humans enabled by upconversion contact lenses.Ma, Y.,et al. Cell, 188(13), 3375-3388(2025)

  • High-Brightness Transition Metal Sensitized High-Brightness Lanthanide Near-Infrared Luminescence Nanoparticles.Ming, J.,et al.Nat. Photon., 18(12), 1254-1262(2024)

  • Fluorescence-Amplified Nanocrystals in the Second Near-Infrared Window For In Vivo Real-Time Dynamic Multiplexed Imaging. Yang, Y., et al. Nat. Nanotechnol., 18(10), 1195-1204(2023)

  • Near-infrared luminescence high-contrast in vivo biomedical imaging. Chen, Y., et al. Nat. Rev.Bioeng., 1(1), 60–78(2023)

  • Deep tissue optical sensing. Lu, L., et al. Nat. Nanotechnol.,17(6), 566(2022)

  • A hybrid erbium(III)–bacteriochlorin near-infrared probe for multiplexed biomedical imaging. Wang, T., et al. Nat. Mater., 20(11), 1571-1578(2021)

  • X-ray-activated persistent luminescence nanomaterials for NIR-II imaging. Pei, P., et al.; Nat. Nanotechnol., 16(9), 1011–1018(2021)

  • Lifetime-engineered NIR-II Nanoparticles Unlock Multiplexed in Vivo Imaging. Fan Y., et al. Nat.Nanotechnol., 13(10), 941-946(2018)

WHY MY LAB?

The Department of Chemistry and the Advanced Materials Laboratory platform of Fudan University, where Fan Zhang is affiliated, hold significant influence both at home and abroad.The facility is equipped with a comprehensive range of large-scale instruments, including High Resolution Field Emission Transmission Electron Microscope, Field Emission Scanning Electron Microscope, X-Ray Diffraction, Upconversion Fluorescence Spectrometer, Near-infrared Fluorescence Spectrometer, Thermal Gravimetric Analyzer, FT-IR and FT-Raman Spectrometers, and Uv Vis NIR spectrum Microspectroscopy. These instruments enable efficient and precise measurements of material properties spectrometers, enables efficient and effective testing and analysis of the morphology, composition, and structure of synthesized near-infrared probes. Additionally, the platform features a fully equipped cell culture room, animal facility, and various cell imaging and in vivo imaging systems (1000–1700 nm), providing students with fundamental experimental conditions for biological research.

Motonari Uesugi

Kyoto University

Japan

Chemical biology, Chemoproteomics, Self-assembly, Chemical immunology

Takeaki Ozawa

The University of Tokyo

Japan

Fluorescence imaging, Bioluminescence analysis, Optogenetics

Midori Arai

Keio University

Japan

Natural products chemistry, Chemical biology, Organic chemistry

Takayoshi Suzuki

The University of Osaka

Japan

Medicinal chemistry, Epigenetics, New modality

Hideaki Kakeya

Kyoto University

Japan

Natural product chemistry, Chemical biology, Medicinal chemistry

Youhei Sohma

Wakayama Medical University

Japan

Peptide chemistry, Amyloid, Catalysis

Hiroyuki Nakamura

Institute of Science Tokyo

Japan

Medicinal chemistry, Cancer therapy, Protein modification

Akio Ojida

Kyushu University

Japan

Chemical biology, Medicinal chemistry

Shinya Hagihara

RIKEN

Japan

Plant chemical biology, Sustainable agriculture, New breeding technology

Masaki Kita

Nagoya University

Japan

Chemical biology, Natural products chemistry, Bioorganic chemistry

Go Hirai

Kyushu University

Japan

Bioorganic chemistry, Organic synthesis, Glycans, Lipids

Tasuku Hirayama

Gifu Pharmaceutical University

Japan

Imaging, Fluorescent probes, Bioinorganic chemistry

Fumika Yakushiji

Nagasaki University

Japan

Chemical epigenetics, Chemical probes, Synthetic organic chemistry, Peptide, Small molecules

Ganesh Pandian Namasivayam

Kyoto University

Japan

Bio-inspired therapeutics, Transcription therapy, Epigenetics

Fumi Nagatsugi

Tohoku University

Japan

Nucleic acids chemistry, Organic chemistry, Chemical biology

Ho Jeong Kwon

Yonsei University

South Korea

Chemical biology, Chemical genomics, Chemical proteomics, Organelle interaction, Autophagy

Sun Choi

Ewha Womans University

South Korea

AI and computer-aided drug design, Computational medicinal chemistry, Drug discovery

Young-Tae Chang

POSTECH

South Korea

Chemical based aging research, Fluorescent imaging, Fluorescent probe, Cell selective probe, Reverse aging

Ja-Hyoung Ryu

UNIST

South Korea

Peptide assembly, PPI mimic, Supramolecular chemistry

Jun-Seok Lee

Seoul National University

South Korea

Fluorescent probe, Chemoproteomics, Drug mode of action

Hyun-Suk Lim

POSTECH

South Korea

Drug discovery, Targeted protein degradation, DNA-encoded library

Yan-Mei Li

Tsinghua University

China

PTMs of protein, Vaccine, cGAS-STING

Ming-Wei Wang

Research Center for Deepsea Bioresources

China

GPCR, PI3K alpha, Structural pharmacology, Drug discovery, Nanobody

Dan Yang

Westlake University

China

Disease mechanism, Fluorescent sensors, Molecular imaging, Proteomics, Drug development

YongXiang Chen

Tsinghua University

China

Protein and peptide chemistry, Protein modification, Phosphorus chemical biology, Biomedical application

Xiaoguang Lei

Peking University

China

Natural product, Chemical genetics, Drug discovery, Biosynthesis, Biocatalysis

Qian Zhao

Hong Kong Polytechnic Univeristy

China

Proteomics, Natural novel peptides, Mass spectrometry

Dehua Yang

Shanghai Institute of Materia Medica, CAS

China

GPCRs, GLP-1R, High-throughput screening, Signal transduction, Receptor pharmacology

Huan Wang

Nanjing University

China

Peptide, Protein, Enzyme, Natural product, Synthetic biology

Xin Zhang

Westlake University

China

Chemical biology, Biological chemistry, Fluorescent microscopy, Synthetic chemistry

Liyun Zhang

Nankai University

China

Synthetic biology, Biosensor, Biocatalysis

Zou Peng

Peking University

China

Proximity labeling, Voltage imaging, Neuroscience, Membraneless organelles

Fan Zhang

Fudan University

China

Rare earth luminescent nanomaterials, NIR, Biomedical analysis

Bengang Xing

The Hong Kong Polytechnic University

China

Chemical biology, Molecular probe & imaging, Bio-labeling, Molecular therapeutics, Nano-theranostics

Jing Yu

Tsinghua University

China

Biophysics, Assembly of biomacromolecules, Condensation of biomolecules

Shi-Zhong Luo

Beijing University of Chemical Technology

China

Bioactive peptide, Cell surface protein phase separation, Peptide drug, Drug delivery

Sandeep Verma

IIT Kanpur

India

Chemical neuroscience, Microfluidic devices, New antibiotics

Govindaraju Thimmaiah

JNCASR

India

Neurodegenerative diseases, Redox biology, Ferroptosis and cuproptosis, Neuroinflammation, Theranostics (diagnostic therapy)

Eylon Yavin

The Hebrew University

Israel

PNA, RNA sensors, Antisense, Fluorogenic dyes

Micha Fridman

Tel Aviv University

Israel

Antimicrobial agents, Fluorescent antifungal probes, Drug resistance and tolerance, Subcellular localization of small molecules

Doron Shabat

Tel Aviv University

Israel

Chemiluminsence, Molecular sensores, Bioorganic chemistry

Yuval Ebenstein

Tel Aviv University

Israel

Genomics and epigenetics, Fluorescence microscopy, Diagnostics

Amir Goldbourt

Tel Aviv University

Israel

Solid state nuclear magnetic resonance, Structural virology, NMR methods and developments

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